Epic Code LAB1231991 Porphobilinogen, 24-Hour Urine Quantitative

Test Name Alias

PorphobUR, Quest: 726

Interface Order Alias

1231991

Clinical Information

Porphobilinogen, Quantitative, 24-Hour Urine - Urinary Porphobilinogen is the first step in the diagnosis of acute porphyrias such as acute intermittent porphyria (AIP). AIP is an autosomal dominant disorder characterized by deficiency of porphobilinogen deaminase. An acute attack usually includes gatrointestinal disturbance and neuropsychiatric disorders.

Specimen Requirements

Specimen Collection Criteria

Collect (preferred specimen): 24-hour urine sample with no preservative.
Keep 24-hour urine specimen iced or refrigerated during collection.

Include start and end dates and times for the collection period on the specimen container.
All specimens must be protected from light during collection.

Physician Office/Draw Specimen Preparation

Protect specimen from light. Maintain specimens refrigerated (2-8°C or 36-46) prior to transport.

In-Lab Processing

Protect specimen from light. Measure total volume of 24-hour urine specimen. Record total volume and collection start and end dates and times in the LIS system. Aliquot 2.0 mL aliquots from the well-mixed 24-hour urine collection and refrigerated (2-8°C or 36-46) . (Minimum: 1.0 mL)

Specimen Transport Temperature

Transport: Entire 24-hour urine collection, or random urine refrigerated (2-8°C or 36-46)

Rejection Criteria

Not protected from light.
Specimens not collected and processed as indicated.

Specimen Stability

Specimen Stability for Testing:
Room Temperature (20-26°C or 68-78.8°F): Unacceptable
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 30 days

Specimen Storage in Department Prior to Disposal:
Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Test Frequency

Performed: Tuesday, Thursday, Saturday
Results available in 3-6 days.

Reference Range

≤17 Years	Not established
≥18 Years	<0.34 mg/24 h

Performing Department

Send Outs

Performing Department Laboratory Location

Sent to Quest Diagnostics- Wood Dale, IL

Methodology

Chromatography/Mass Spectrometry.

CPT

84110

LOINC

Unavailable

Reviewed Date

11/8/2025

Orderable Regions