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Epic Code LAB10163 Proteinase 3 Antibody (PR3)

Test Name Alias

PR3 Antibody | Antineutrophil Cytoplasmic Antibodies | Wegener’s Granulomatosis | 193

Interface Order Alias

11550

Collection Instructions

Specimen Collection: Blood

Container(s): Gold Top (Serum Separator-SST Gel)

Preferred Volume to Collect: 5.0 mL

Minimum Volume to Collect: 2.0 mL

Neonate Volume to Collect: 2.0 mL

Capillary collect ok: Yes

Microtainer acceptable: Yes

Collection Instructions:

  • Gently invert gold tube(s) 8 - 10 times to mix clot activator with blood.
  • Specimen should be processed within 2 hours – See Processing Instructions.

Processing Instructions (Laboratory, Outpatient or Off-site collection)

Processed Specimen: Serum

Centrifuge/Spin: Yes

Aliquot: No

Processing Instructions:

  • Allow blood to clot for 30 minutes in a vertical position and centrifuge within 2 hours.

Transport Temperature: Refrigerate

Rejection Criteria

Specimen not centrifuged within 2 hours

Specimen Stability

Ambient: 12 hours

Refrigerate: 7 days

Frozen: aliquot serum for longer storage

Laboratory Retention: 7 days

Test Frequency

Test performed Monday - Friday with usual TAT 1 to 3 days

Reference Range

Reference Range ≤0.3 Al

Comments

Below 0.4 U/ml Negative
0.4-0.9 U/ml Equivocal
1.0 or above U/ml Positive

If positive or equivocal, recommend ANCA test if not already performed, or if MPO/PR3 result is negative and ANCA associated diseases are clinically suspected. Additional physician order is required for ANCA test.

Performing Department

Immunochemistry

Performing Department Laboratory Location

Corewell Health Reference Laboratory, Grand Rapids, MI

Methodology

Multiplex Flow Assay

CPT

83516

CDM Code

3018351624

Epic Test ID

1230101064

LOINC

PR3 Ab: 46267-1

Mayo Access Code

SHO193

Reviewed Date

12/13/2022