Epic Code LAB1230940 HLA-DQB1*06:02 Genotyping (Narcolepsy)
Test Name Alias
HLA-DQB1 06:02; NARCOLEPSY; HLA Class II Disease Association; Narcolepsy-Associated Antigen, HLA-DQB1 Typing, Blood
Quick Collect
+WB/A
Invert several times to mix well.
Shipping/Handling Instructions: Do not refrigerate or freeze specimen. Maintain whole blood at room temperature (20-26°C or 68-78.8°F) prior to transport. Transport to the Laboratory within 72 hours of collection.
Specimen Type
Blood
Collection Instructions
Specimen Collection: Blood
Container(s): 6 mL Pink Top (EDTA) or TWO 3 mL Lavender Top (EDTA)
Preferred Volume to Collect: 6.0 mL
Collection Instructions:
- Gently invert EDTA tube(s) 8 - 10 times after collection.
Processing Instructions (Laboratory, Outpatient or Off-site collection)
- Processed Specimen: Whole Blood
- Centrifuge/Spin: No
- Aliquot: No
- Do not refrigerate or freeze specimen. Maintain whole blood at room temperature (20-26°C or 68-78.8°F) prior to transport. Transport to the Laboratory within 72 hours of collection.
- Transport: Ambient
In-Lab Processing
Maintain specimen at room temperature (20-26°C or 68-78.8°F) until testing.
Specimen Stability
Specimen Stability for Testing:
Room Temperature (20-26°C or 68-78.8°F): 72 hours
Refrigerated (2-8°C or 36-46°F): Unacceptable
Frozen (-20°C/-4°F or below): Unacceptable
Specimen Storage in Department Prior to Disposal:
Frozen (-80°C): 2 years (DNA)
Test Frequency
As needed.
Results typically available within 5 business days.
Reference Range
Interpretation by report.
Performing Department
Send out to Corewell Health East
Performing Department Laboratory Location
Corewell Health East Royal Oak HLA Laboratory
Methodology
Polymerase Chain Reaction (PCR).
CPT
81376
CDM Code
CDM
Epic Test ID
1230102609
Reviewed Date
1/1/2025
Clinical Information
HLA Class II genotyping defines the antigens of the HLA-DRB1 and DQB1 loci of the Major Histocompatibility Complex found on the short arm of chromosome 6. Using DNA extracted from leukocytes, HLA-DRB1 and DQB1 alleles are amplified via PCR using sequence-specific primers. After amplification, the specific HLA antigens are determined by gel electrophoresis for disease association purposes.
Rejection Criteria
Specimens drawn in green, clot, or SST tubes are unacceptable and will not be tested. Unlabeled specimens will be rejected.
Updated Date
3/12/2025 - Clinical Information and Rejection Criteria added