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HELPFUL LINKS!

 

LAB COMMUNICATIONS 

 

COLLECTION & HANDLING

 

SPECIMEN TRANSPORTATION

Please call 616.774.7721 for specimen pick up

 

GENERAL INFORMATION

 

GENERAL TEST INFORMATION

 

BILLING

 

WEBSITES

Mayo Clinic Laboratories

Epic Code LAB12310394 Rheumatoid Factor

Test Name Alias

RA | RF

Interface Order Alias

12310394

Clinical Information

Rheumatoid factors are a heterogeneous group of autoantibodies directed against the antigenic determinants on the Fc‑region of IgG molecules. They are important in the diagnosis of rheumatoid arthritis but can also be found in other inflammatory rheumatic diseases and in various non‑rheumatic diseases. They are also found in clinically healthy people over 60 years of age. Despite these restrictions, the detection of rheumatoid factors is a diagnostic criterion of the American College of Rheumatology for classifying rheumatoid arthritis.

 

These autoantibodies occur in all immunoglobulin classes (IgA, IgG, and IgM). This assay measures all three types of autoantibodies for a total rheumatoid factor result.

Collection Instructions

Specimen Collection: Blood

Container(s):

  • CHW: Gold Top (Serum Separator-SST Gel)
  • CHS: Mint Green Top (Lithium Heparin Gel) or Gold Top (Serum Separator-SST Gel)

Minimum Volume to Collect: 2.0 mL

Neonate Volume to Collect: 2.0 mL

Capillary collect ok: Yes

Microtainer acceptable: Yes

Collection Instructions:

  • Gently invert gold tube(s) 8-10 times
  • Specimen should be processed within 2 hours – See Processing Instructions.

 

Processing Instructions (Laboratory, Outpatient or Off-site collection)

  • Processed Specimen:
    • CHW: Serum
    • CHS: Plasma or Serum
  • Centrifuge/Spin: Yes
  • Aliquot: No
  • Processing Instructions: 
    • Gold/Serum: Allow blood to clot for 30 minutes in a vertical position and centrifuge within 2 hours.
    • Green/Plasma: Centrifuge after collection.
  • Transport Temperature: Refrigerate

Specimen Transport Temperature

Refrigerated

Specimen Stability

Ambient: 24 hours

Refrigerate: 8 days

Frozen: 3 months frozen (freeze only once)

Laboratory Retention: 7 days

Test Frequency

Test run daily

Reference Range

<14 IU/mL

Performing Department

CHEMISTRY

Performing Department Laboratory Location

CHW: Corewell Health Reference Laboratory, Grand Rapids, MI
CHS: Corewell Health Lakeland St. Joseph Laboratory, St. Joseph, MI

Methodology

Immunoturbidimetric

CPT

86431

CDM Code

3028643101

Epic Test ID

Unknown

LOINC

11572-5

Mayo Access Code

Unknown

Reviewed Date

3/7/2024

Updated Date

5/28/2025 - CHS info added