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LAB COMMUNICATIONS 

 

COLLECTION & HANDLING

 

SPECIMEN TRANSPORTATION

Please call 616.774.7721 for specimen pick up

 

GENERAL INFORMATION

 

GENERAL TEST INFORMATION

 

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Mayo Clinic Laboratories

Epic Code LAB1231256 S. Cerevisiae Ab, IgA/IgG

Additional Codes

ARUP: 0050564

Interface: 1231256

Test Name Alias

XSACG | XSACA | SC PAN

Ordering Instructions

May aid in the diagnosis of Crohn disease. Test by itself is not diagnostic and should be used in conjunction with other parameters to confirm disease. 

Collection Instructions

Specimen Collection: Blood

 

Container(s): Gold Top Serum Separator Tube (SST)

Preferred Volume to Collect: 5 mL

Minimum Volume to Collect: 1.0 mL

 

Collection Instructions:

  • Gold/Serum: Allow blood to clot for 30 minutes in a vertical position and centrifuge within 2 hours.

 

PROCESSING INSTRUCTIONS

Separate serum from cells ASAP or within 2 hours of collection.

Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Specimen Transport Temperature

Refrigerated

Rejection Criteria

  • Contaminated
  • Hemolyzed
  • Severely lipemic
  • Heat-inactivated

Specimen Stability

After separation from cells

Ambient: 48 hours

Refrigerate: 2 weeks

Frozen: 1 year (avoid repeated freeze/thaw cycles)

Test Frequency

Available Sun-Sat reported in 1-2 days after receipt at ARUP Lab

Reference Range

Test Number Components Reference Interval
  S. cerevisiae Antibody, IgG
20.0 Units or less Negative
20.1-24.9 Units Equivocal
25.0 Units or greater Positive

 
  S. cerevisiae Antibody, IgA
20.0 Units or less Negative
20.1-24.9 Units Equivocal
25.0 Units or greater Positive

 

 

Interpretive Data

Saccharomyces cerevisiae IgG antibodies are found in 60-70% of Crohn disease (CD) patients and 10-15% of ulcerative colitis (UC) patients. Saccharomyces cerevisiae IgA antibodies are found in about 35% of CD patients but less than 1% in UC patients. Detection of both Saccharomyces IgG and IgA antibodies in the same serum specimen is highly specific for CD.

Performing Department

Send out to ARUP Ref. Lab

Performing Department Laboratory Location

REFERRAL SEND OUTS

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

CPT

86671 x2

CDM Code

3028667103 

Epic Test ID

123010447

LOINC

Component Test Code* Component Chart Name LOINC
0050562 S. cerevisiae Antibody, IgG 47321-5
0050563 S. cerevisiae Antibody, IgA 47320-7

* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Reviewed Date

4/2/2025 - Added to catalog