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Epic Code LAB1231780 Beta CTX-I (Cross Laps) 

Test Name Alias

C-Telopeptide, C-terminal collagen crosslinks, Carboxy terminal collagen crosslinks, CTX, 7162,LAB3656 | 1230102984

Interface Order Alias

1231780

Quick Collect

+(1)S/PO/F

Clinical Information

During renewal of the skeleton, Type I collagen is degraded and small peptide fragments are excreted into the bloodstream. These fragments can be measured by Beta Cross Laps.

Collection Instructions

Specimen Collection: Blood

 

Container(s): Gold Top (Serum Separator-SST Gel); Red Top (plain)

Preferred Volume to Collect: 5.0 mL

Minimum Volume to Collect: 2.0 mL

Neonate Volume to Collect: 2.0 mL

Capillary collect ok? Yes

Microtainer acceptable: Yes

 

Collection Instructions:

  • Fasting patient is preferred, but not required.

  • After collection, gently invert tube 8-10 times.

  • Specimen should be processed within 1 hour. See processing instructions

 

Processing Instructions (Laboratory, Outpatient or Off-site collection)

  • Processed Specimen: Serum
  • Centrifuge/Spin: Yes
    • Allow blood to clot for 30 minutes in a vertical position and centrifuge promptly.
  • Aliquot: Yes
    • Within 1 hour aliquot serum into a plastic transport tube and freeze immediately.
  • Transport Temperature: Frozen

Specimen Transport Temperature

Frozen Serum

 

Rejection Criteria

  • Specimen not centrifuged promptly after collection.
  • Centrifuged serum not meeting specimen stability requirements.

 

Specimen Stability

Add-on allowed? No

 

If not frozen within 1 hour, see below.

  • Ambient: 8 hours
  • Refrigerated: 24 hours
  • Frozen: 28 days
  • Laboratory Retention: 7 days

Test Frequency

Test run Mondays through Fridays, usual turn around time 1 to 3 days.

 

Reference Range

Female Pediatric Reference Range

  • ≤6 years: 179 - 1690 pg/mL
  • 7 – 11 years: 300 - 1978 pg/mL
  • 12 – 16 years: 151 - 1912 pg/mL
  • 17 – 21 years: 109 - 1130 pg/mL

Male Pediatric Reference Range

  • ≤6 years: 446 - 1756 pg/mL
  • 7 – 11 years: 659 - 1975 pg/mL
  • 12 – 16 years: 393 - 2131 pg/mL
  • 17 – 21 years: 263 -1554 pg/mL

Adult Female and Male Reference Range:

  • Females premenopausal (greater than 21 years old to 55 years old): 121 to 747 pg/mL
  • Females postmenopausal (greater than 55 years old): 189 to 1003 pg/mL
  • Males greater than 21 years old: 154 to 771 pg/mL

 

Performing Department

Immunochemistry

Performing Department Laboratory Location

Corewell Health Reference Laboratory, Grand Rapids, MI

Methodology

Chemiluminescence

CPT

82523

CDM Code

3018252301

Epic Test ID

 1230102984

LOINC

41171-0

Reviewed Date

3/4/2025

Updated Date

1/24/2025 - Reference Range (312)

7/14/2025 - Specimen Stability (354)

Orderable Regions

Southwest; West