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Mayo Clinic Laboratories

Epic Code LAB1231792 Cardiolipin Antibodies (IgG, IgM)

Test Name Alias

Anti-phospholipid Antibody | Anti-cardiolipin Screen | Cardiolipin Screen | LAB3653 | Cardiolipin Antibodies, IgG and IgM | 55115

Interface Order Alias

1231792

Clinical Information

Cardiolipin IgG/IgM and Beta Glycoprotein 1 IgG/IgM Antibodies when used in conjunction with other clinical findings, aid in the diagnosis of primary Antiphospholipid Syndrome (APS) and those secondary to systemic lupus erythematosus (SLE) or SLE-like disorders. Antibody profiles are encouraged to identify thrombotic risk and may be more useful than individual tests in identifying a patient's risk.

Panel Information

This test is part of Panel: Antiphospholipid Antibody Syndrome Panel [LAB1230572] 

Collection Instructions

Specimen Collection: Blood

Container(s): Gold Top (Serum Separator-SST Gel)

Preferred Volume to Collect: 5.0 mL

Minimum Volume to Collect: 2.0 mL

Neonate Volume to Collect: 2.0 mL

Capillary collect ok: Yes

Microtainer acceptable: Yes

Collection Instructions:

  • After collection, gently invert tube 8-10 times.
  • Specimen should be processed within 2 hours – See Processing Instructions.

 

Processing Instructions (Laboratory, Outpatient or Off-site collection)

  • Processed Specimen: Serum
  • Centrifuge/Spin: Yes
  • Aliquot: No
  • Processing Instructions: Allow blood to clot for 30 minutes in a vertical position and centrifuge within 2 hours.
  • Transport Temperature: Refrigerate

Rejection Criteria

Specimen not centrifuged within 2 hours

Specimen Stability

Ambient: 12 Hours

Refrigerate: 7 days (2-8° C)

Frozen: -20°C for longer storage

Laboratory Retention: 7 days

Test Frequency

Test available Monday - Friday. Turn-around time 1 - 3 days.

Reference Range

both IgG and IgM:

<20 U/mL Negative

≥ 20 U/mL Positive

Performing Department

Immunochemistry

Performing Department Laboratory Location

Corewell Health Reference Laboratory, Grand Rapids, MI

Methodology

Multiplex Flow Immunoassay

CPT

86147, 86147

CDM Code

3028614701, 3028614701

Epic Test ID

1230100444

Mayo Access Code

Not available

Reviewed Date

12/13/2022

Updated Date

12/26/2024 - Order Name, Order Code