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HelpEpic Code LAB1231841 Toxoplasma Antibodies (IgG, IgM)
Test Name Alias
LAB501 | LAB659 | 10267 | TORCH, TORC, TOXOPLASMOSIS, TOXOPLASMA GONDII IGG, TOXOPLASMA GONDII ANTIBODIES, IGG
Interface Order Alias
1231841
Clinical Information
- Intended for the qualitative detection of IgG anitobodies Toxoplasma gondii.
- Intended as an aid in the diagnosis of current or recent Toxoplasma gondii infection, including women of child-bearing age.
- Per the FDA, IgM positive results by a screening assay should be confirmed, for example with Toxoplasma PCR method.
Collection Instructions
Specimen Collection: Blood
- Container(s): Gold Top (Serum Separator-SST Gel)
- Preferred Volume to Collect: 5.0 mL
- Minimum Volume to Collect: 1.0 mL
- Neonate Volume to Collect: 1.0 mL
- Capillary collect ok: Yes
- Microtainer acceptable: Yes
-
Collection Instructions:
- Gently invert gold tube(s) 8 - 10 times to mix clot activator with blood.
- Specimen should be processed within 2 hours – See Processing Instructions.
Processing Instructions
- Processed Specimen: Serum
- Centrifuge/Spin: Yes
- Aliquot: No
- Minimum Serum Volume: 1.0 mL
- Processing Instructions: Allow blood to clot for 30 minutes in a vertical position and centrifuge within 2 hours.
- Transport Temperature: Refrigerate
Rejection Criteria
Specimen not centrifuged within 2 hours
Specimen Stability
Ambient: 3 days
Refrigerate: 7 days
Frozen: aliquot serum for longer storage at-20C or colder
Laboratory Retention: 7 days
Test Frequency
Available Monday through Friday, usual TAT 1-3 days.
Reference Range
Negative
Toxoplasmosis IgG & IgM Interpretation
|
T. gondii IgG Result |
T. gondii IgM Result |
Result Interpretation |
|---|---|---|
|
Negative |
Negative |
No serologic evidence of infection with T. gondii |
|
Negative |
Equivocal |
Possible early acute infection or false-positive IgM reaction. Obtain a new specimen for IgG and IgM testing. If the new specimen result remains the same, the patient is probably a false-positive. |
|
Negative |
Positive |
Possible acute infection or false-positive IgM result. Obtain a new specimen for IgG and IgM testing. If results from the second specimen remain the same, the IgM reaction is probably a false-positive. |
|
Equivocal |
Negative |
Equivocal: obtain a new specimen for both IgG and IgM testing. |
|
Equivocal |
Equivocal |
Equivocal: obtain a new specimen for both IgG and IgM testing. |
|
Equivocal |
Positive |
Possible acute infection with T.gondii. Obtain a new specimen for IgG and IgM testing. If results with the new specimen remain the same or the IgG becomes positive, both specimens should be sent to a reference laboratory with experience in the diagnosis of toxoplasmosis. |
|
Positive |
Negative |
Infected with T. gondii for more than one year. |
|
Positive |
Equivocal |
Infected with T. gondii for probably more than one year or false-positive IgM reaction. Obtain a new specimen for IgG and IgM testing. If results from the second specimen remain the same, both specimens should be sent to a reference laboratory with experience in the diagnosis of toxoplasmosis. |
|
Positive |
Positive |
Possible recent infection within the last 12 months. Send the specimen to a reference laboratory with experience in the diagnosis of toxoplasmosis. |
*Adapted from FDA Publication: “Limitations of Toxoplasma IgM commercial Test Kits” July 25,1997
Performing Department
Immunochemistry
Performing Department Laboratory Location
Corewell Health Reference Laboratory, Grand Rapids, MI
Methodology
Multiplex Flow Immunoassay
CPT
86777
86778
CDM Code
3028677701
3028677801
Epic Test ID
1230102992
LOINC
5388-4
Toxoplas Ab IgM: 40678-5
Mayo Access Code
Unavailable
Reviewed Date
New Test 12/2024