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Mayo Clinic Laboratories

Epic Code LAB1231870 Pancreatic Elastase, Fecal

Important Note

Corewell Health Reference Laboratory East Test

Pancreatic enzyme supplementation therapy should be discontinued prior to collection.

Test Name Alias

Fecal Elastase, E1, Pancreatic Elastase, Random Stool

Clinical Information

To aid in the diagnosis of pancreatic exocrine insufficiency.

Specimen Requirements

Specimen Collection: Stool

 

Container(s): Sterile container 

Minimum Volume to Collect: 1.0 g

 

Collection Instructions:

  • Pancreatic enzyme supplementation therapy should be discontinued prior to collection.

Specimen Transport Temperature

Refrigerated  (2°– 8°C)

Rejection Criteria

  • Stool collected from diaper.
  • Specimens not collected and processed as indicated.

Specimen Stability

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 8 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 12 months

Specimen Storage in Department Prior to Disposal: Specimens retained for 72 hours after testing.

Test Frequency

Monday, Wednesday, Friday.
Results available within 3-5 business days.

Reference Range

<100 mcg/g (Severe Exocrine Pancreatic Insufficiency).

100-199 mcg/g (Mild to Moderate Exocrine Pancreatic Insufficiency).

≥200 mcg/g (Normal Exocrine Pancreatic Function).

 

Interpretation

Decreased amounts of pancreatic elastase in feces are not diagnostic for exocrine pancreatic insufficiency (EPI) and normal concentrations do not exclude the possibility of EPI.

Consistency of raw fecal sample may affect analytical performance.

Performing Department

Royal Oak Special Chemistry Laboratory

Performing Department Laboratory Location

REFERRAL SEND OUTS

Methodology

Chemiluminescence

CPT

82653

CDM Code

3018265302 

Epic Test ID

1230103018

Reviewed Date

Added 4/8/2025