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HelpEpic Code LAB1231927 Histone Antibody, IgG
Test Name Alias
LAB1231715 | Histone Ab | Quest: 37056 | Anti-Histone Antibody, AHA
Interface Order Alias
1231927
Clinical Information
Histone Antibodies - Histone antibody is present in 80-95% of patients with drug-induced Systemic Lupus Erythematosus (SLE), 20-50% of patients with idiopathic SLE, and infrequently in patients with other autoimmune connective tissue diseases.
Specimen Requirements
- Overnight fasting preferred.
Specimen Collection Criteria
Collect: One Gold-top SST tube.
Also Acceptable: One plain Red-top tube.
Physician Office/Draw Specimen Preparation
Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to plastic transport tube and maintain at refrigerate (2-8°C or 36-46) prior to transport.
In-Lab Processing
Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to plastic transport tube and maintain at refrigerate (2-8°C or 36-46) prior to transport.
Specimen Transport Temperature
Transport: 1.0 mL serum , refrigerated (2-8 °C or 36-46 °F). (Minimum : 0.3mL)
Rejection Criteria
- Specimen not collected and processed as indicated..
Specimen Stability
Specimen Stability for Testing:
Room Temperature (20-26°C or 68-78.8°F): 24 hours
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 30 days
Specimen Storage in Department Prior to Disposal:
Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.
Test Frequency
Performed: Wednesday, Friday.
Results available 3-6 days.
Reference Range
|
Value |
Explanation of Results |
|
<1.0 |
Negative |
|
1.0-1.5 |
Weak Positive |
|
1.6-2.5 |
Moderate Positive |
|
>2.5 |
Strong Positive |
Performing Department
Send Outs
Performing Department Laboratory Location
Sent to Quest Diagnostics- Wood Dale, IL
Methodology
Enzyme Immunoassay (EIA)
CPT
83516
LOINC
43231-0
Reviewed Date
11/2/2025
Orderable Regions
Send Outs