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Epic Code LAB196 Protein, Body Fluid

Test Name Alias

Protein Body Fluid | BFL | 8264

Interface Order Alias

10458

Ordering Instructions

Ascites, Elbow (Left or Right), Hip (Left or Right), Joint (Ankle, Elbow, Finger, Hip, Knee, Other, Shoulder, Toe, Wrist), Knee (Left or Right), Pericardial, Peritoneal, Pleural Cavity (Left or Right), Shoulder (Left or Right), Synovium/Bursa, or Wrist (Left or Right) will be performed at Corewell Health Reference Laboratory West.

 

If your source does not match the above, please order a Reference Miscellaneous Test and list the desired test and specimen source and type.

Collection Instructions

Specimen Collection: Body Fluid

 

Container(s): Clear top tube, no additive

Preferred Volume to Collect: Full tube 

Minimum Volume to Collect: 0.5 mL

 

Collection Instructions:

  • Indicate source.
    • Ascites, Elbow (Left or Right), Hip (Left or Right), Joint (Ankle, Elbow, Finger, Hip, Knee, Other, Shoulder, Toe, Wrist), Knee (Left or Right), Pericardial, Peritoneal, Pleural Cavity (Left or Right), Shoulder (Left or Right), Synovium/Bursa, or Wrist (Left or Right) will be performed at Corewell Health Reference Laboratory West.
    • If your source does not match the above, please order a Reference Miscellaneous Test and list the desired test and specimen source and type.

Processing Instructions (Laboratory, Outpatient or Off-site collection)

Transport Temperature: Refrigerate

Specimen Stability

Ambient: 8 hours

Refrigerate: 72 hours

Frozen: aliquot for longer storage

Laboratory Retention: 4 days

Test Frequency

Available daily, usual TAT 1 day.

Reference Range

Reference range not established for body fluids.

 

Pericardial protein: "Biochemical analysis of pericardial fluid (pH, total protein, glucose, LD) is of limited clinical value in most cases. Light's criteria, originally established for pleural effusions, have been shown to classify nearly all pericardial fluids as exudates regardless of etiology. (Am J Cardiol. 2007;99(9):1294; Heart. 2020;106(7):541.)

 

Pleural protein: "Pleural fluid TP/serum TP ratio of greater than 0.5 or pleural fluid total protein level greater than 3.0 g/dL is consistent with exudate. Pleural fluid TP/serum TP ratio of less than or equal to 0.5 or pleural fluid total protein level less than or equal to 3.0 g/dL is consistent with transudate. Using total protein alone misclassifies exudates and transudates in about 30% of cases. Sensitivity and specificity increase to 98% and 80%, respectively, when using both total protein and LD criteria.

 

Peritoneal protein: "Transudates: < 3.0 g/dL Exudates: => 3.0 g/dL The Serum-Ascites Albumin Gradient has been proposed as the more effective test in the differential diagnosis of ascites.

 

This test was developed and its performance characteristics determined by Corewell Health Laboratories. It has not been cleared or approved by the FDA. This test is used for clinical purposes. It should not be regarded as investigational or for research. The reference range and other method performance specifications have not been established for this body fluid. The test result must be integrated into the clinical context for interpretation.”

Performing Department

Chemistry

Performing Department Laboratory Location

Corewell Health Reference Laboratory, Grand Rapids, MI

Methodology

Colorimetric – Biuret

CPT

84157

CDM Code

3018415701

Epic Test ID

1230101080

LOINC

Specimen Type: 66746-9

Protein BFL: 2881-1

Mayo Access Code

SHO10458

Reviewed Date

3/7/2024

Updated Date

3/18/2024 - Reference Range

5/20/2024 - Collection Container updated from Mint or Red to Clear