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Epic Code LAB2111030 Codeine/Morphine Levels

Test Name Alias

Codeine/Morphine Blood Level | 4051

Interface Order Alias


Collection Instructions

Specimen Collection: Blood


Container(s): Gray Top (Potassium Oxalate and Sodium Fluoride) or Red top (no additive)

Uscreen and iSCREEN POC (Point of Care) urine drug testing cups are acceptable but not preferred

Preferred Volume to Collect: 3.0 mL

Minimum Volume to Collect: 2.0 mL

Neonate Volume to Collect: 2.0 mL

Capillary collect ok? Yes

Microtainer acceptable?  Yes


Collection Instructions:

  • After collection, gently invert tube 8-10 times.
  • Gray Top is preferred tube.
  • Specimen should be processed – See Processing Instructions.

Processing Instructions (Laboratory, Outpatient or Off-site collection)

Processed Specimen: Plasma or Serum

Centrifuge/Spin: Yes

Aliquot: Yes


Processing Instructions:

  • Gray top:
    • Centrifuge after collection
    • Pipette plasma into aliquot tubes
  • Red top:
    • When tubes are clotted (30-45 minutes), centrifuge specimens
    • Pipette serum into aliquot tube

Minimum plasma/serum volume: 1.0 mL


Transport Temperature: Ambient

Specimen Stability

Ambient: 72 hours

Refrigerate: 7 days

Frozen: 14 days

Laboratory Retention: 7 days

Test Frequency

Available daily, usual TAT 1-3 days.

STAT TAT 6 hours.

Reference Range

Codeine Level 10 - 100 ng/mL

Morphine Level 21 - 65 ng/mL

Performing Department


Performing Department Laboratory Location

Corewell Health Reference Laboratory, Grand Rapids, MI


Liquid Chromatography-Mass Spectrometry


This test was developed and its performance characteristics determined by Spectrum Health Toxicology Laboratory. It has not been cleared or approved by the FDA. The laboratory is regulated under CLIA as qualified to perform high-complexity testing. This test is used for clinical purposes. It should not be regarded as investigational or for research.




80361, G0480

CDM Code


Epic Test ID



Codeine Lvl: 3506-3

Morphine Lvl: 3827-3

Mayo Access Code


Additional Information

Gold Top SST not acceptable

Reviewed Date