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Epic Code LAB309 Factor XI Activity

Important Note

There is currently a nationwide shortage of this tube. Please take steps to ensure specimen integrity to reduce recollection. Specimen Tube Shortage (link)

Test Name Alias

Factor XI (11) Activity | 8191 | Factor 11

Interface Order Alias

10136

Quick Collect

+(1)S10POx3/F

Clinical Information

Useful for the diagnosis of congenital (Hemophilia C) or acquired Factor XI deficiency.  May be used to clarify prolonged activated partial thromboplastin time.  Acquired Factor XI deficiency may be associated with liver disease.  Acquired Factor XI deficiency is rarely associated with inhibitors.  

Collection Instructions

Specimen Collection: Blood

 

Container(s): 3.2% Na Citrate Tube (blue top)

Preferred Volume to Collect: 2.7 mL (full tube)

Minimum Volume to Collect: 1.8 mL (full tube)

Capillary collect ok: No

Microtainer acceptable: No

 

Collection Instructions:

Processing Instructions (Laboratory, Outpatient or Off-site collection)

Processed Specimen: Platelet Poor Plasma with a platelet count <10 X 109/L

 

Centrifuge/Spin: Yes

Aliquot: Yes

 

Processing Instructions:

  • Detailed instructions (link): Preparing Platelet Poor Plasma
  • Separate plasma into 2 - 3 aliquots, minimum of 0.5 mL each.
  • Freeze aliquots in plastic transport tubes immediately.

Transport Temperature:

  • Ambient (up to 1 hour in whole blood state)
  • Frozen (plasma only >1 hours)

Rejection Criteria

  • Hemolysis
  • Specimen has been thawed

Specimen Stability

Ambient: 1 hour

Frozen: 2 months

Laboratory Retention: 2 months

Test Frequency

Available Monday – Friday, usual TAT 1-4 days.

Reference Range

Adult: 50 – 150 %

 

Pediatric reference ranges have not been established.

 

Critical Values Table

Performing Department

Coagulation

Performing Department Laboratory Location

Corewell Health Reference Laboratory, Grand Rapids, MI

Methodology

Activated Partial Thromboplastin (APTT) clot based assay with plasma deficient substrate

CPT

85270

CDM Code

3058527001

Epic Test ID

1230100674

LOINC

Factor XI Activity: 3226-8

Mayo Access Code

SHO8191

Reviewed Date

3/23/2023