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Epic Code LAB3295 Bacterial Overgrowth, Breath Test

Important Note

Test Name Alias

Bacterial Overgrowth Breath Test | H2 Breath Test for Bacterial Overgrowth | Hydrogen Breath Test | 4131

Interface Order Alias

11613

Quick Collect

Schedule before draw

Clinical Information

This test was developed and its performance characteristics determined by Spectrum Health Laboratory. It has not been cleared or approved by the FDA. The laboratory is regulated under CLIA as qualified to perform high-complexity testing. This test is used for clinical purposes. It should not be regarded as investigational or for research.

Ordering Instructions

Test must be ordered prior to scheduling.

Collection Instructions

Improper specimen collection can adversely affect the outcome of the test. Specimen collection should only be performed by staff with experience in proper specimen collection procedures.

 

Patient will consume Lactulose (gluten free)

 

Specimen collection: Alveolar, air from properly prepared patient who ingested lactulose

Container(s): Collection bags (7 total)

Minimum volume: 40 mL

 

LINK: Patient Preparation

 

For pediatric patients weighing 21 pounds (9.5 kg) or less:

  1. Contact the Corewell Health West Helen DeVos Children’s Pharmacy at (616) 267-1807 with the amount of lactulose that needs to be measured from the formula below.
  2. Pour 15 mL of LACTULOSE 10gm/15mL into 8 ounces (240mL) of water.
  3. Measure 1 ounce (30mL) of the diluted lactulose solution (from step 2) per 10 pounds of the child’s weight (up to 21 pounds) and administer this amount for the BacterialOvergrowth test.
  4. Example: If a child weighs 18 pounds, give the child 2 ounces (60mL) of lactulose solution. (18 pounds divided by 10 = 2 ounces)
  5. Walk LACTULOSE to Corewell Health West HDVCH Pharmacy (Room #89101 – 8th floor) and pharmacy staff will measure the correct amount of lactulose.

 

If questions on the amount of lactulose solution to give a pediatric patient weighing 9.5 kg (21 pounds) or less than, call Immunochemistry Department at (616) 267-2770.

Specimen Stability

Ambient: 6 hours

Test Frequency

By schedule only, test is available Monday – Friday. Usual TAT 1-2 days.

Reference Range

Bacterial overgrowth in the small intestine is suggested if the Breath H2 increases at least 20 ppm within the first 2 hours (due to bacterial breakdown in the small intestine) followed by a larger H2 breath increase once the lactulose reaches the colon. In some patients double peaks do not appear but the levels plateau instead.

Performing Department

Immunochemistry

Performing Department Laboratory Location

Corewell Health Reference Laboratory, Grand Rapids, MI

Methodology

Gas chromatograph

CPT

91065

CDM Code

9209106501

Epic Test ID

1230100370

Reviewed Date

12/13/2022

Updated Date

11/15/2024 - Collection and Processing Pediatric Patients (286)