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Epic Code LAB3542 Hepatitis C Antibody Screening

Important Note

The Hepatitis C Antibody Screening orderable should be used when the test is ordered for the following screening purposes:

  • Patients in the “baby boom” generation (born between 1945 and 1965) where the CDC has specifically recommended screening (one time only)
  • Patients with a history of blood transfusions prior to 1992 (one time only)
  • Intravenous drug abusers (annually with continued abuse)
  • Routine screening in pregnant individuals (ACOG practice advisory)

Test cannot be ordered as an add-on

Test Name Alias

Hepatitis C | Antibody Level | Hepatitis C Antibody Screening | HCV | Hepatitis C Ab Lvl | 7058

Interface Order Alias


Clinical Information

Results with a Roche assay index reading predictive of 95% or greater probability of being true positives will be reported as Reactive.  False positive results are expected to occur in less than 5% of specimens with such results.


Specimens with Reactive Hepatitis C Antibody results will be automatically reflexed to the quantitative Hepatitis C Virus RNA test, per a new mandatory Laboratory reflex testing policy which has been approved by the Medical Executive Committee. This test can be performed on the same specimen used for the Hepatitis C Antibody test, and no new physician order will be needed.


The quantitative Hepatitis C Virus RNA test may serve as a baseline for Hepatitis C Virus antiviral therapy. CDC (Centers for Disease Control) and other current guidelines recommend the Hepatitis C Virus RNA test as a follow-up for positive Hepatitis C Antibody results.


It should be noted that Hepatitis C Genotyping may be indicated for guidance of antiviral therapy in patients with newly diagnosed Hepatitis C Virus infection. A new physician order Hepatitis C Genotype with Amplification SH#4434 is required for this test.


Collection Instructions

Specimen Collection: Blood


Container(s): 5.0 mL Gold Top (Serum Separator-SST Gel)

  • Preferred Volume to Collect: 5.0 mL
  • Minimum Volume to Collect: 2.0 mL
  • Neonate Volume to Collect: 1.0 mL
  • Capillary collect ok? Yes
  • Microtainer acceptable: Yes 


Collection Instructions:

  • Gently invert 5 times to mix clot activator with blood.
  • Specimen should be processed within 2 hours – See Processing Instructions.



Processing Instructions (Laboratory, Outpatient or Off-site collection)

Processed Specimen: Serum

Centrifuge/Spin: Yes

Aliquot: Yes

Minimum volume: 1.0 mL serum

Processing Instructions:

  • Allow blood to clot for 30 minutes in a vertical position and centrifuge within 2 hours.

Transport Temperature: Refrigerate

Specimen Transport Temperature


Specimen Stability

Ambient: 8 hours

Refrigerate: 72 hours

Frozen: aliquot serum for longer storage

Laboratory Retention: 72 hours

Reflex Information

Reflex approved by MEC

  • Specimens with Reactive Hepatitis C Antibody results will be automatically reflexed to the quantitative  Hepatitis C Virus RNA test

Test Frequency

Available 24 hours, usual TAT 1 day

Reference Range


Performing Department


Performing Department Laboratory Location

Corewell Health Reference Laboratory, Grand Rapids, MI




86803, 86803, G0472

CDM Code

3028680302, 3028680302

Epic Test ID



Not available

Mayo Access Code


Reviewed Date