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Epic Code LAB3621 IgE Brazil Nut Component Add-On

Test Name Alias

allergen | ImmunoCAP | Allergen Specific IgE | RAST | Allergy | Tree Nut | 7104

Interface Order Alias

55035

Clinical Information

IgE antibodies to rBer e 1 (Brazil Nut Storage Protein) are associated with systemic reactions to brazil nuts.

 

Component testing for Brazil Nut must be ordered as follow-up to whole allergen results.This test is not available as a reflex test. Patient specimens are stored frozen for 30 days.

 

Component testing measures IgE antibodies to individual proteins unlike whole allergen testing which measures the presence of specific immunoglobulin E (sIgE) antibodies to a combination of allergenic and non-allergenic proteins. This next generation testing identifies the source of sensitization and helps the clinician assess the risk of systemic reaction.

 

Results of component testing can assist with patient selection for oral food challenge as well as possible management recommendations such as immunotherapy and/or allergen avoidance/food elimination.  Because of the diagnostic and management complexities associated with food allergy, referral to an allergy and immunology specialist should be considered when evaluating a patient with suspected food allergies.

Specimen Requirements

Specimen Collection: Blood

Container(s): Gold Top (Serum Separator-SST Gel)

Preferred Volume to Collect: 3.0 mL

Minimum Volume to Collect: 2.0 mL

Neonate Volume to Collect: 2.0 mL

Capillary collect ok? Yes

Microtainer acceptable? Yes

 

Processed specimen: Serum

Centrifuge/Spin: Y

Aliquot: N

Processing instructions: Allow specimen to clot for 30 minutes and centrifuge within 2 hours.

Specimen Transport Temperature

Refrigerate

Rejection Criteria

Quantity not sufficient (QNS)

Specimen Stability

Serum

Ambient: 12 hours

Refrigerate: 7 days

Frozen: aliquot for longer storage

Laboratory Retention: 30 days

Test Frequency

Available Monday through Friday, usual TAT 1-3 days.

Reference Range

<0.35 kU/L

Performing Department

Immunochemistry

Performing Department Laboratory Location

Corewell Health Reference Laboratory, Grand Rapids, MI

Methodology

ImmunoCAP® System Fluorescence Enzyme Immunoassay (FEIA)

CPT

86008

CDM Code

3028600801

Epic Test ID

1230101922

Mayo Access Code

SHO55035

Reviewed Date

3/4/2024

Updated Date

3/17/2024 – Reference Range (OEE)