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Epic Code LAB3643 MYD88 Mutation Analysis

Test Name Alias

MDY88 Mutation Analysis | 7134

Interface Order Alias


Quick Collect


Clinical Information

MYD88 mutation L265P is essential to differentiate Waldenstrom macroglobulinemia/Lymphoplasmacytic Lymphoma  (WM/LPL) from non-IgM B cell lymphomas and plasma cell myeloma.

Specimen Requirements

Submit only one specimen type*:


*Specimen Type: Bone Marrow

Container/Tube: Lavender top or Pink top (EDTA)

Volume: 3.0 mL

Minimum volume: 1.0 mL


*Specimen Type: Whole Blood

Container/Tube: Lavender top or Pink top (EDTA)

Volume: 3 mL

Minimum volume: 1.0 mL

Pediatric volume: 1.0 mL (2 microtainers)

Okay for capillary collect? Yes


*Specimen Type: Formalin-fixed, paraffin-embedded tissue (FFPE) Bone Marrow clot

Collection Instructions: Area of interest marked on block or accompanying H&E slide.

Specimen Transport Temperature


Specimen Stability


Whole Blood/Bone Marrow

Ambient: 72 hours

Refrigerate: 7 days

Frozen: Not Available

Laboratory Retention: Extracted DNA retained greater than 1 year


FFPE Bone Marrow Clot

Ambient: Forever

Laboratory Retention: Extracted DNA retained greater than 1 year

Reflex Information

Pathologist reflex order

Test Frequency

Performed once per week

Usual turn-around time, less than 7 days

Reference Range

An interpretative report will be provided.

Performing Department

Molecular Diagnostics

Performing Department Laboratory Location

Corewell Health Advanced Technology Laboratory (ATL), Grand Rapids, MI


Next generation sequencing by Ion AmpliSeq technology



CDM Code


Epic Test ID


Mayo Access Code


Reviewed Date