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HelpEpic Code LAB458 ANCA (Anti Neutrophil Cytoplasmic Antibody)
Test Name Alias
ANCA | cANCA | Wegener’s | Anticytoplasmic Autoantibodies | p ANCA | pANCA | 8556 | Granulomatosis
Interface Order Alias
10089
Clinical Information
Includes c-ANCA (cytoplasmic) and p-ANCA (perinuclear)
Positive c-ANCA results are titered, with ≥1:20 considered positive
Collection Instructions
Specimen Collection: Blood
Container(s): Gold Top (Serum Separator-SST Gel)
Preferred Volume to Collect: 5.0 mL
Minimum Volume to Collect: 1.0 mL
Neonate Volume to Collect: 1.0 mL
Capillary collect ok: Yes
Microtainer acceptable: Yes
Collection Instructions:
- After collection, gently invert tube 8-10 times.
- Specimen should be processed within 2 hours – See Processing Instructions.
Processing Instructions (Laboratory, Outpatient or Off-site collection)
Processed Specimen: Serum
Centrifuge/Spin: Yes
Aliquot: No
Processing Instructions:
- Allow blood to clot for 30 minutes in a vertical position and centrifuge within 2 hours.
Transport Temperature: Refrigerate
Rejection Criteria
Specimen not centrifuged within 2 hours
Specimen Stability
Ambient: 12 hours
Refrigerate: 7 days
Frozen: aliquot plasma/serum for longer storage
Laboratory Retention: 7 days
Test Frequency
Available Monday through Friday, usual TAT 1 to 3 days.
Reference Range
Negative < 1:20
Positive c-ANCA results are titered, with ≥1:20 considered positive
Performing Department
Immunochemistry
Performing Department Laboratory Location
Corewell Health Reference Laboratory, Grand Rapids, MI
Methodology
Immunofluorescence Assay (IFA)
CPT
86036
CDM Code
3028603601
Epic Test ID
1230100342
LOINC
c-ANCA: 35279-9
p-ANCA: 17357-5
p-ANCA Comment: 48767-8
Mayo Access Code
SHO8556
Reviewed Date
12/13/2022