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HelpEpic Code LAB501 Toxoplasma Antibody, IgG
Test Name Alias
Toxoplasmosis | Toxoplasma gondii IgG | Torch | ToRC
Interface Order Alias
10267
Clinical Information
Intended for the qualitative detection of IgG anitobodies Toxoplasma gondii.
Collection Instructions
Specimen Collection: Blood
Container(s): Gold Top (Serum Separator-SST Gel)
Preferred Volume to Collect: 5.0 mL
Minimum Volume to Collect: 1.0 mL
Neonate Volume to Collect: 1.0 mL
Capillary collect ok: Yes
Microtainer acceptable: Yes
Collection Instructions:
- Gently invert gold tube(s) 8 - 10 times to mix clot activator with blood.
- Specimen should be processed within 2 hours – See Processing Instructions.
Processing Instructions (Laboratory, Outpatient or Off-site collection)
Processed Specimen: Serum
Centrifuge/Spin: Yes
Aliquot: No
Minimum Serum Volume: 1.0 mL
Processing Instructions:
- Allow blood to clot for 30 minutes in a vertical position and centrifuge within 2 hours.
Transport Temperature: Refrigerate
Rejection Criteria
Specimen not centrifuged within 2 hours
Specimen Stability
Ambient: 3 days
Refrigerate: 7 days
Frozen: aliquot serum for longer storage at-20C or colder
Laboratory Retention: 7 days
Test Frequency
Available Monday through Friday, usual TAT 1-3 days.
Reference Range
Negative
Results Interpretation
| Results | Interpretation |
|---|---|
| Negative | Patient is presumed not to have had a previous T. gondii infection |
| Equivocal | Equivocal results: obtain an additional sample for re-testing |
| Positive | IgG Antibody to T.gondii detected which may indicated current or pat T.gondii infection |
Toxoplasmosis IgG & IgM Interpretation
|
T. gondii IgG Result |
T. gondii IgM Result |
Result Interpretation |
|---|---|---|
|
Negative |
Negative |
No serologic evidence of infection with T. gondii |
|
Negative |
Equivocal |
Possible early acute infection or false-positive IgM reaction. Obtain a new specimen for IgG and IgM testing. If the new specimen result remains the same, the patient is probably a false-positive. |
|
Negative |
Positive |
Possible acute infection or false-positive IgM result. Obtain a new specimen for IgG and IgM testing. If results from the second specimen remain the same, the IgM reaction is probably a false-positive. |
|
Equivocal |
Negative |
Equivocal: obtain a new specimen for both IgG and IgM testing. |
|
Equivocal |
Equivocal |
Equivocal: obtain a new specimen for both IgG and IgM testing. |
|
Equivocal |
Positive |
Possible acute infection with T.gondii. Obtain a new specimen for IgG and IgM testing. If results with the new specimen remain the same or the IgG becomes positive, both specimens should be sent to a reference laboratory with experience in the diagnosis of toxoplasmosis. |
|
Positive |
Negative |
Infected with T. gondii for more than one year. |
|
Positive |
Equivocal |
Infected with T. gondii for probably more than one year or false-positive IgM reaction. Obtain a new specimen for IgG and IgM testing. If results from the second specimen remain the same, both specimens should be sent to a reference laboratory with experience in the diagnosis of toxoplasmosis. |
|
Positive |
Positive |
Possible recent infection within the last 12 months. Send the specimen to a reference laboratory with experience in the diagnosis of toxoplasmosis. |
*Adapted from FDA Publication: “Limitations of Toxoplasma IgM commercial Test Kits” July 25,1997
Performing Department
Immunochemistry
Performing Department Laboratory Location
Corewell Health Reference Laboratory, Grand Rapids, MI
Methodology
Multiplex Flow Immunoassay
CPT
86777
CDM Code
3028677701
Epic Test ID
1230102180
LOINC
5388-4
Mayo Access Code
Unavailable
Reviewed Date
12/13/2022