Sign in →

Epic Code LAB7130 Cryoglobulin, Serum

Important Note

  • During transportation keep the tubes wrapped in an activated Instant Hot Pack- Medium

  • Due to collection and handling of the specimen, it is required patients be collected at an outpatient draw site that is located inside a Hospital. 

  • Read all collection and processing instructions or call ImmunoChemistry at (616) 267-2770.
  • Cryoglobulin cannot be ordered a second time within a 2 week window in the Laboratory Information System (LIS).

 

Test Name Alias

Cryoglobulins | 8128 | SHO8128 | 1230100539

Interface Order Alias

10117

Quick Collect

LOOK+LOOK

Clinical Information

This test was developed and its performance characteristics determined by Spectrum Health Laboratory. It has not been cleared or approved by the FDA. The laboratory is regulated under CLIA as qualified to perform high-complexity testing. This test is used for clinical purposes. It should not be regarded as investigational or for research.

Collection Instructions

Specimen Collection: Blood

Container(s): Red Top (Plain, No additive) x 4

  • Preferred Volume to Collect: 24.0 mL
  • Minimum Volume to Collect: 8.0 mL
  • Neonate Volume to Collect: 8.0 mL
  • Capillary collect ok: Yes
  • Microtainer acceptable: Yes

Collection Instructions:

  • Deliver to lab immediately after collection.
  • During transportation keep the tubes wrapped in an activated Instant Hot Pack- Medium to maintain at or near body temperature before and during the clotting process.
  • Recommend that outpatient specimens be drawn at a Hospital Laboratory.

 

Processing Instructions (Laboratory, Outpatient or Off-site collection)

 

Processed Specimen: Serum

Centrifuge/Spin: Yes

Aliquot: Yes

Processing Instructions:

  • Upon receipt in the lab, transfer the tubes to a 37º C water bath. Do not completely immerse the tubes under water, but the water level must surround the blood level in the tube.
  • After tubes clot (approx. 45 mins) centrifuge for 5 minutes, combine serum into one tube and centrifuge again.
  • Transfer serum to plastic transport tube and refrigerate.
  • This specimen must be free of all red cells.

Transport Temperature: Refrigerate after processing

Rejection Criteria

  • Frozen specimen

Specimen Stability

Deliver to laboratory immediately. Refrigerate after processing.

Reflex Information

Mandatory Reflex Testing (link):

  • Positive Cryoglobulin which have not had an identification in the past 12 months will have Reflex Cryoglobulin Interpretation ordered.

 

Test Frequency

Available Monday through Friday, usual TAT 4-7 days.

Reference Range

No cryoglobulin detected.

 

Positive cryoglobulin reported with Pathologist interpretation

Performing Department

Immunochemistry

Performing Department Laboratory Location

Corewell Health Reference Laboratory, Grand Rapids, MI

Methodology

Positive cryoglobulin are identified using agarose gel immunofixation

CPT

86334
Additional charges for pathologist interpretations may apply.

CDM Code

3018259501

Epic Test ID

1230100539

LOINC

Cryoglobulin: 5117-7

Cryoglobulin type in serum by immunofixation: 48638-1

Mayo Access Code

SHO8128

Reviewed Date

3/4/2025

Updated Date

1/13/2025 - Important Note BW removed

3/28/2025 - Important Note added utilization information

5/2/2025 - Rejction criteria added

Orderable Regions

Southwest; West