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Epic Code LAB7580 Factor X Activity

Important Note

Therapeutic doses of hirudin or other direct thrombin inhibitors lead to erroneous lower factor activity. To evaluate low molecular weight heparin (LMWH) anti-xa please order LMWH. To evaluate unfractionated heparin please order Unfractionated Heparin Level.

This test is for factor X activity, not to be confused with anti-xa inhibitor therapy.

There is currently a nationwide shortage of this tube. Please take steps to ensure specimen integrity to reduce recollection. Specimen Tube Shortage (link)

Test Name Alias

Factor X (10) Activity | 4274 | Factor 10 | Factor ten

Interface Order Alias

10376

Quick Collect

+(1)S10POx3/F

Clinical Information

Useful for the diagnosis of congenital or acquired factor X deficiency.  Also effective in the evaluation of protein synthesis in liver disease.  May be used to clarify a prolonged prothrombin time or activated partial thromboplastin time. 

Collection Instructions

Specimen Collection: Blood

 

Container(s): 3.2% Na Citrate Tube (blue top)

Preferred Volume to Collect: 2.7 mL (full tube)

Minimum Volume to Collect: 1.8 mL (full tube)

Capillary collect ok: No

Microtainer acceptable: No

 

Collection Instructions:

Processing Instructions (Laboratory, Outpatient or Off-site collection)

Processed Specimen: Platelet Poor Plasma with a platelet count <10 X 109/L

 

Centrifuge/Spin: Yes

Aliquot: Yes

 

Processing Instructions:

  • Detailed instructions (link): Preparing Platelet Poor Plasma
  • Separate plasma into 2 - 3 aliquots, minimum of 0.5 mL each.
  • Freeze aliquots in plastic transport tubes immediately.

Transport Temperature:

  • Ambient (up to 1 hour in whole blood state)
  • Frozen (plasma only >1 hour)

Rejection Criteria

  • Hemolysis
  • Specimen has been thawed

Specimen Stability

Ambient: 1 hour

Frozen: 2 months

Laboratory Retention: 2 months

Test Frequency

Available Monday - Friday, usual TAT 1-4 days.

Reference Range

Adult: 50 – 150 %

 

Pediatric reference ranges have not been established.

 

Critical Values Table

Performing Department

Coagulation

Performing Department Laboratory Location

Corewell Health Reference Laboratory, Grand Rapids, MI

Methodology

Prothrombin (PT) clot based assay with plasma deficient substrate

CPT

85260

CDM Code

3058526001

Epic Test ID

1230100673

LOINC

Factor X Activity: 3218-5

Mayo Access Code

SHO10376

Reviewed Date

3/23/2023