Epic Code LAB8340 Prothrombin G20210A
Test Name Alias
Prothrombin G20210A | Factor II G20210A | PT G20210A | Factor II Mutation | Prothrombin Mutation | Prothrombin G20210 | Prothrombin Mutation Analysis | 78 | PT2
Interface Order Alias
10510
Quick Collect
+A
Clinical Information
Detects point mutation G20210A in the prothrombin gene, and is suggested for patients with inherited thrombophilia.
Patients on heparin therapy and blood transfusion patients may have blood specimens that potentially interfere leading to invalid or erroneous results
Ordering Instructions
Prothrombin G20210A is a predictive and presymptomatic genetic test.
Submission of an order for any predictive genetic tests and presymptomatic genetic tests, as defined by MCL 333.17020, contained in this catalog constitutes certification to Corewell Health laboratories that the ordering physician understands that written, informed consent is required for these tests and that, by submitting an order for these genetic tests, ordering physician has obtained “Informed Consent” of subject patient as required by any applicable state or federal laws with respect to each test ordered. On occasion, we forward a specimen to an outside reference laboratory. Corewell Health laboratories may request that ordering physician provide such consent to Corewell Health upon a reasonable request.
For an example of an informed consent, click here.
This test should only be resulted once per lifetime. The duplicate checking indicates that this
patient has already had this testing performed. Please see chart review for results.
If unable to order, please call the appropriate lab area for assistance.
Collection Instructions
Specimen Collection: Blood
Container(s): Lavender Top (EDTA) 3.0 mL
Preferred Volume to Collect: 3.0 mL
Minimum Volume to Collect: 1.0 mL
Neonate Volume to Collect: 1.0 mL
Collection Instructions:
- Gently invert 8 - 10 times after collection.
- For optimal results, specimen should be received within 24 hours of collection. Send specimen same day of collection.
-
If one or more of the following tests are ordered simultaneously, only one EDTA tube needs to be collected:
- Factor V Leiden DNA Analysis
- Prothrombin G20210A
Processing Instructions (Laboratory, Outpatient or Off-site collection)
- Processed Specimen: Whole Blood EDTA
- Centrifuge/Spin: No
- Aliquot: No
- Transport Temperature: Ambient
Rejection Criteria
This test should only be resulted once per lifetime.
Specimen Stability
Ambient: 24 hours
Refrigerated: 15 days
Laboratory Retention: 3 months
Test Frequency
Available at least twice per week, usual TAT 3 – 5 days.
Reference Range
Negative
Performing Department
Molecular Diagnostics
Performing Department Laboratory Location
Corewell Health Advanced Technology Laboratory (ATL), Grand Rapids, MI
Methodology
Multiplex Polymerase Chain Reaction (PCR) followed by detection using scorpion probes
CPT
81240
CDM Code
3108124001
Epic Test ID
1230101098
LOINC
Prothrombin G20210A: 24475-6
Prothrombin G20210A Interp: 8251-1
Mayo Access Code
SHO078
Reviewed Date
6/22/2023