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Epic Code LAB848 NGAL (Neutrophil Gelatinase-Associated Lipocalin)

Important Note

Order as Reference Miscellaneous #LAB848; indicate complete test name when ordering.

Interface Order Alias

1230499

Collection Instructions

Specimen Collection: Urine (Random)

 

Container(s): Sterile Urine Cup or Pale Yellow Top Urine Tube or Tube no additive or Clear-top no additive

Preferred Volume to Collect: 2 mL

Minimum Volume to Collect: 1 mL

Neonate Volume to Collect: 1 mL

 

Collection Instructions:

  • No preservatives
  • Keep container upright at all times and check that lid is fastened evenly and securely.
  • Patient Collection Instructions are located in the menu on the left.

Processing Instructions (Laboratory, Outpatient or Off-site collection)

Processed Specimen: Random Urine (2 mL)

Centrifuge/Spin: Yes

Aliquot: No

Transport Temperature: Refrigerated

Specimen Stability

Ambient: Up to 24 hours at 15-28⁰ C

Refrigerate: Up to 48 hours 2-8⁰ C

Frozen: Greater than 24 hours should be frozen at -20⁰ C or below.   For longer storage -70⁰ C or below is recommended.

Laboratory Retention: 3 days

Test Frequency

Available 24 hours

Reference Range

NGAL in early acute kidney injury (AKI)– Suggested Approach

  • <50 ng/mL – Low risk of AKI. This result does not exclude subsequent development of AKI; repeat if clinically indicated.
  • 50-149 ng/mL – Equivocal risk of AKI; repeat measurement is indicated if clinically justified.
  • 150-300 ng/mL – Moderate risk of AKI; test result has high sensitivity/moderate specificity.
  • >300 ng/mL – High risk of AKI; test result has high specificity.

Kidney Int Rep (2017) 2, 1243–1249; http://dx.doi.org/10.1016/j.ekir.2017.05.012

 

This test was developed and its performance characteristics determined by Spectrum Health Regional Laboratory.  It has not been cleared or approved by the FDA.  This laboratory is regulated under CLIA as qualified to perform high-complexity testing.  This test is used for clinical purposes in conjunction with other medical diagnostic procedures.

Performing Department

Referrals

Performing Department Laboratory Location

Cincinnati Children's Hospital 

 

Methodology

Particle Enhanced Turbimetric Immunoassay

CPT

83520

CDM Code

80105987

Epic Test ID

N/A

LOINC

Not available - Contact Helpdesk

Mayo Access Code

Not available - Contact Helpdesk

Resources

Collection Guide: Patient Home Collection Guide

Urine Vacutainer Training: Specimen Collection - Urine Vacutainer (Yellow tube)

Reviewed Date

6/9/2023