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Mayo Clinic Laboratories

Epic Code LAB848 COVID-19 IgG, Qualitative by CIA

Important Note

Order as Reference Miscellaneous #LAB848; indicate complete test name when ordering.

Use for the qualitative detection of IgG antibodies against the nucleocapsid protein of SARS-CoV-2 (COVID-19) that develop in response to natural infection with SARS-CoV-2. These antibodies do not develop as a result of a COVID-19 vaccination.  

Recommended utilization limited to aid in the clinical diagnosis of multisystem inflammatory syndrome in children or adults (MIS-C or MIS-A).  

Additional Codes

ARUP Code: 3002776

Clinical Information

Use for the qualitative detection of IgG antibodies against the nucleocapsid protein of SARS-CoV-2 (COVID-19) that develop in response to natural infection with SARS-CoV-2. These antibodies do not develop as a result of a COVID-19 vaccination. There are no current recommendations for assessing COVID-19 vaccine response.

Collection Instructions

Container(s): Gold top (Serum Separator SST)  or EDTA plasma

Preferred Volume to Collect: 1.5 mL

Minimum Volume to Collect: 1 mL

Submission Container/Tube:  Plastic vial

Collection Instructions:

  • After collection, gently invert tube 8-10 times.
  • Specimen should be processed ASAP or within 2 hours – See Processing Instructions below.

 

 

PROCESSING INSTRUCTIONS (Laboratory, Outpatient or Off-site collection)

Processed Specimen: Serum or Plasma

Centrifuge/Spin: Yes

Aliquot: Yes

Processing Instructions:

  • Allow blood to clot for 30 minutes in a vertical position and centrifuge promptly.
  • Within two hours aliquot serum or plasma into a plastic transport tube and refrigerate as soon as possible.
  • (+(2)S/PO/R)

Specimen Transport Temperature

Refrigerated

Rejection Criteria

Grossly hemolyzed, lipemic or severely lipemic specimens. Postmortem specimens.

Specimen Stability

Serum Specimens (Pour-Overs)

Refrigerated: 1 week

Frozen: 1 month

Test Frequency

Monday, Wednesday, Friday.
Results available within 5 business days.

Reference Range

Negative

Performing Department Laboratory Location

ARUP Laboratory

 

Methodology

Qualitative Chemiluminescent Immunoassay (CLIA)

CPT

86769

Reviewed Date

08/23/2023